General Anatomy & Embryology · NEET PG Preparation Anatomy
A 2-day-old newborn is evaluated for congenital anomalies. Echocardiography reveals a persistent truncus arteriosus. This cardiac defect arises prima…
Practice question from General Anatomy & Embryology (NEET PG Preparation Anatomy), with the correct answer and a step-by-step solution.
medium · MCQ · Q-00B0DE
A 2-day-old newborn is evaluated for congenital anomalies. Echocardiography reveals a persistent truncus arteriosus. This cardiac defect arises primarily due to the abnormal development or failure of which of the following cell populations?
- A.Paraxial mesoderm
- B.Neural crest cellsCorrect answer
- C.Splanchnic mesoderm
- D.Endocardial cushion cells
Solution
Persistent truncus arteriosus results from the failure of neural crest cells to migrate properly into the bulbus cordis and truncus arteriosus, which are responsible for forming the aorticopulmonary septum that divides the outflow tract into the aorta and pulmonary trunk.
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