Neural Control and Coordination · NEET Preparation Zoology

A drug selectively blocks voltage-gated Ca2+ channels in the presynaptic membrane of a chemical synapse. What is the most immediate consequence when…

Practice question from Neural Control and Coordination (NEET Preparation Zoology), with the correct answer and a step-by-step solution.

hard · MCQ · Q-1DC3E1

A drug selectively blocks voltage-gated Ca2+ channels in the presynaptic membrane of a chemical synapse. What is the most immediate consequence when an action potential reaches the axon terminal?

  1. A.The action potential cannot travel along the axon
  2. B.Synaptic vesicles cannot release neurotransmitter into the synaptic cleftCorrect answer
  3. C.The postsynaptic membrane remains permanently depolarised
  4. D.The neurotransmitter is released continuously without stimulation

Solution

Arrival of an action potential at the axon terminal opens voltage-gated Ca2+ channels. The resulting Ca2+ influx triggers fusion of synaptic vesicles with the presynaptic membrane and neurotransmitter release. Blocking these channels prevents this release.

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