Anxiety & Personality Disorders · NEET PG Preparation Psychiatry

A 32-year-old woman is brought to the emergency department experiencing a sudden onset of intense fear, palpitations, chest pain, shortness of breath…

Practice question from Anxiety & Personality Disorders (NEET PG Preparation Psychiatry), with the correct answer and a step-by-step solution.

medium · MCQ · Q-28FA27

A 32-year-old woman is brought to the emergency department experiencing a sudden onset of intense fear, palpitations, chest pain, shortness of breath, dizziness, and a profound fear of dying. The episode peaked within 10 minutes and subsided after about 30 minutes. She reports having had several similar unexpected episodes over the past month, accompanied by persistent worry about having another attack. Which neurotransmitter system is primarily implicated in the pathophysiology of this condition and targeted by acute benzodiazepine treatment?

  1. A.Dopaminergic
  2. B.GABAergicCorrect answer
  3. C.Serotonergic
  4. D.Cholinergic

Solution

The patient is presenting with Panic Disorder. Panic disorder involves dysregulation of the GABA-benzodiazepine receptor complex, where GABA is the primary inhibitory neurotransmitter. Benzodiazepines enhance GABA-A receptor activity to rapidly reduce acute anxiety.

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