Cardiovascular System · NEET PG Preparation Physiology
A 65-year-old patient is diagnosed with severe aortic stenosis. Which of the following pressure-volume loop alterations is expected in this patient?
Practice question from Cardiovascular System (NEET PG Preparation Physiology), with the correct answer and a step-by-step solution.
hard · MCQ · Q-2E867A
A 65-year-old patient is diagnosed with severe aortic stenosis. Which of the following pressure-volume loop alterations is expected in this patient?
- A.Shift of the entire loop to the left with decreased end-systolic volume
- B.Increased end-diastolic volume with a shifted end-diastolic pressure-volume relationship curve
- C.Increased peak systolic left ventricular pressure with a markedly narrowed pulse pressureCorrect answer
- D.Increased stroke volume due to prolonged ejection time
Solution
In aortic stenosis, the left ventricle must generate a significantly higher pressure to eject blood through the narrowed valve against an increased afterload. This manifests as a much taller pressure-volume loop with greatly increased peak systolic left ventricular pressure.
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