Principles of Inheritance and Variation · Class 12 · CBSE · Science Biology

Which of the following conditions correctly describes the chromosomal aberration responsible for Down's syndrome?

Practice question from Principles of Inheritance and Variation (Class 12 · CBSE · Science Biology), with the correct answer and a step-by-step solution.

medium · MCQ · Q-4629DE

Which of the following conditions correctly describes the chromosomal aberration responsible for Down's syndrome?

  1. A.Monosomy of sex chromosomes (45, X)
  2. B.Trisomy of chromosome 21Correct answer
  3. C.Trisomy of sex chromosomes (47, XXY)
  4. D.Deletion of the short arm of chromosome 5

Solution

Down's syndrome is a chromosomal disorder caused by the presence of an extra copy of chromosome 21, known as trisomy 21.

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