Parasitology · NEET PG Preparation Microbiology

A 32-year-old HIV-positive patient with a CD4 count of 50 cells/uL presents with severe headache and confusion. Brain MRI shows multiple ring-enhanci…

Practice question from Parasitology (NEET PG Preparation Microbiology), with the correct answer and a step-by-step solution.

hard · MCQ · Q-79BA0D

A 32-year-old HIV-positive patient with a CD4 count of 50 cells/uL presents with severe headache and confusion. Brain MRI shows multiple ring-enhancing lesions with surrounding edema. He owns a pet cat. Which of the following is the definitive diagnostic method or primary finding for the most likely organism?

  1. A.Crescent-shaped tachyzoites seen in CSF smear or brain biopsyCorrect answer
  2. B.Trypomastigotes in peripheral blood smear
  3. C.Oocysts identified via modified acid-fast staining of stool
  4. D.Flask-shaped trophozoites with ingested RBCs

Solution

The patient has cerebral toxoplasmosis caused by Toxoplasma gondii. Histologically, it is characterized by crescent-shaped tachyzoites and tissue cysts containing bradyzoites visible in brain tissue or CSF.

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