General Microbiology & Sterilisation · NEET PG Preparation Microbiology

What is the primary mechanism of action of alcohol (such as 70 percent isopropyl alcohol) as an antiseptic and disinfectant?

Practice question from General Microbiology & Sterilisation (NEET PG Preparation Microbiology), with the correct answer and a step-by-step solution.

medium · MCQ · Q-81BCE1

What is the primary mechanism of action of alcohol (such as 70 percent isopropyl alcohol) as an antiseptic and disinfectant?

  1. A.Alkylation of nucleic acids
  2. B.Denaturation of proteins and disruption of cell membranesCorrect answer
  3. C.Inhibition of cell wall synthesis by binding to transpeptidases
  4. D.Oxidation of essential sulfhydryl groups

Solution

Alcohols act primarily by denaturing proteins and dissolving lipids, leading to cell membrane disruption. They require water to be effective, which is why 70% alcohol is more effective than absolute (100%) alcohol.

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