Head & Neck Oncology · NEET PG Preparation ENT

A 45-year-old male with a history of betel nut chewing presents with restricted mouth opening (trismus) and a firm, white, non-scrapable mucosal plaq…

Practice question from Head & Neck Oncology (NEET PG Preparation ENT), with the correct answer and a step-by-step solution.

easy · MCQ · Q-A2F40A

A 45-year-old male with a history of betel nut chewing presents with restricted mouth opening (trismus) and a firm, white, non-scrapable mucosal plaque on the buccal mucosa. Histopathology reveals epithelial dysplasia with subepithelial fibrosis. What is the most definitive diagnosis?

  1. A.Oral hairy leukoplakia
  2. B.Oral submucous fibrosis with leukoplakiaCorrect answer
  3. C.Actinic cheilitis
  4. D.Squamous cell papilloma

Solution

Oral submucous fibrosis (OSMF) is a chronic debilitating condition strongly associated with betel nut/areca nut chewing, characterized by progressive trismus and mucosal fibrosis. Coexistent leukoplakia with dysplasia represents a high risk for malignant transformation into squamous cell carcinoma.

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