Leprosy · NEET PG Preparation Dermatology
A 28-year-old male treated for borderline tuberculoid leprosy 3 months ago presents with acute swelling, redness, and tenderness of pre-existing skin…
Practice question from Leprosy (NEET PG Preparation Dermatology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-A982D6
A 28-year-old male treated for borderline tuberculoid leprosy 3 months ago presents with acute swelling, redness, and tenderness of pre-existing skin lesions, along with acute tenderness and loss of function in the right ulnar nerve. Skin smear is negative. What is the diagnosis and mechanism?
- A.Type 1 reaction; Delayed-type hypersensitivity (Cell-mediated)Correct answer
- B.Type 2 reaction; Immune complex-mediated
- C.Type 3 reaction; Immediate hypersensitivity
- D.Lucio phenomenon; Thrombotic vasculopathy
Solution
Type 1 reaction (Reversal reaction) is a delayed-type (Type IV) hypersensitivity reaction occurring in borderline spectrum leprosy (BT, BB, BL). It is characterized by acute inflammation of existing skin lesions and neuritis, without systemic signs like ENL.
More from Leprosy
- A 35-year-old male presents with multiple hypopigmented, anesthetic patches over his trunk and extremities. Skin slit smear is positive for…
- A patient with lepromatous leprosy on Multi-Drug Therapy (MDT) develops painful subcutaneous nodules on the extremities, accompanied by fev…
- Which of the following nerves is classically known to be the most commonly affected peripheral nerve in leprosy?
- According to the World Health Organization (WHO) guidelines, what is the standard duration of Multi-Drug Therapy (MDT) for a patient diagno…
Practise more Dermatology
Sign up free for adaptive practice on this chapter, with instant feedback and hints on every question.
Start practising freeFree to start · No credit card needed