Infections of Skin · NEET PG Preparation Dermatology
A 10-year-old child presents with honey-colored crusted lesions around the nose and mouth. Removal of the crusts reveals an erythematous, moist base.…
Practice question from Infections of Skin (NEET PG Preparation Dermatology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-BF9757
A 10-year-old child presents with honey-colored crusted lesions around the nose and mouth. Removal of the crusts reveals an erythematous, moist base. Which of the following toxins produced by the causative organism is primarily responsible for the development of bullous impetigo?
- A.Erythrogenic toxin
- B.Exfoliative toxin A and BCorrect answer
- C.Toxic shock syndrome toxin-1 (TSST-1)
- D.Panton-Valentine leukocidin
Solution
Bullous impetigo is caused by Staphylococcus aureus strains that produce exfoliative toxins (ETA and ETB). These serine proteases target desmoglein 1 in the superficial epidermis, leading to blister formation.
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