Haemodynamic Disorders · NEET PG Preparation Pathology
A 62-year-old female undergoes prolonged surgery and develops microvascular thrombosis in multiple organs, accompanied by severe bleeding from venipu…
Practice question from Haemodynamic Disorders (NEET PG Preparation Pathology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-C7786B
A 62-year-old female undergoes prolonged surgery and develops microvascular thrombosis in multiple organs, accompanied by severe bleeding from venipuncture sites. Laboratory tests reveal prolonged PT and PTT, low fibrinogen, and elevated D-dimer. Which pathological process best explains these findings?
- A.Primary fibrinolysis
- B.Disseminated intravascular coagulationCorrect answer
- C.Thrombotic thrombocytopenic purpura
- D.Hemophilia A
Solution
Disseminated intravascular coagulation (DIC) is characterized by widespread systemic activation of the coagulation cascade, leading to the formation of microthrombi in small blood vessels (consuming platelets and clotting factors) and secondary activation of fibrinolysis, resulting in bleeding and elevated D-dimers.
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