Complications of Pregnancy · NEET PG Preparation Obstetrics & Gynaecology

A 26-year-old G2P1 at 10 weeks of gestation presents with severe nausea and vomiting, inability to retain any food or fluids, and a 6 kg weight loss…

Practice question from Complications of Pregnancy (NEET PG Preparation Obstetrics & Gynaecology), with the correct answer and a step-by-step solution.

medium · MCQ · Q-073743

A 26-year-old G2P1 at 10 weeks of gestation presents with severe nausea and vomiting, inability to retain any food or fluids, and a 6 kg weight loss since her last visit. Laboratory investigations reveal hypokalemic metabolic alkalosis and moderate ketonuria. Which of the following vitamin deficiencies is most critical to prevent Wernicke encephalopathy when initiating intravenous dextrose therapy?

  1. A.Vitamin B1 (Thiamine)Correct answer
  2. B.Vitamin B6 (Pyridoxine)
  3. C.Vitamin B12 (Cobalamin)
  4. D.Vitamin C (Ascorbic acid)

Solution

In hyperemesis gravidarum, prolonged vomiting can lead to severe nutritional depletion. Administering intravenous fluids containing dextrose without prior thiamine supplementation can precipitate acute Wernicke encephalopathy. Thiamine (Vitamin B1) must be given before any carbohydrate load.

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