Carbohydrate Metabolism · NEET PG Preparation Biochemistry
During high-intensity anaerobic exercise, skeletal muscle generates large amounts of lactate. This lactate is transported via the blood to the liver,…
Practice question from Carbohydrate Metabolism (NEET PG Preparation Biochemistry), with the correct answer and a step-by-step solution.
hard · MCQ · Q-0DE2DF
During high-intensity anaerobic exercise, skeletal muscle generates large amounts of lactate. This lactate is transported via the blood to the liver, where it is converted back into glucose to maintain blood glucose levels. What is the net ATP cost (in equivalents) required by the liver to synthesize one molecule of glucose from two molecules of lactate via this cycle?
- A.2 ATP
- B.4 ATP
- C.6 ATPCorrect answer
- D.8 ATP
Solution
The Cori cycle involves the conversion of glucose to lactate in muscle (yielding 2 ATP) and the reconversion of 2 lactates to glucose in the liver via gluconeogenesis, which consumes 6 ATP equivalents.
More from Carbohydrate Metabolism
- A 6-month-old infant is brought to the emergency department with recurrent episodes of severe fasting hypoglycemia, hepatomegaly, and doll-…
- An adult male presents with chronic fatigue and dark pigmentation of the sclera (ochronosis). He also reports that his urine turns dark upo…
- A 45-year-old chronic alcoholic is brought to the hospital in an unarousable state following a binge-drinking episode. He has not eaten for…
- Which of the following regulatory molecules acts as a potent allosteric activator of phosphofructokinase-1 (PFK-1) in the liver, signaling…
Practise more Biochemistry
Sign up free for adaptive practice on this chapter, with instant feedback and hints on every question.
Start practising freeFree to start · No credit card needed