Human Health and Disease · NEET Preparation Zoology

Which molecular change can directly convert a normal proto-oncogene into an oncogene and promote uncontrolled cell proliferation?

Practice question from Human Health and Disease (NEET Preparation Zoology), with the correct answer and a step-by-step solution.

hard · MCQ · Q-1B95E5

Which molecular change can directly convert a normal proto-oncogene into an oncogene and promote uncontrolled cell proliferation?

  1. A.A mutation that causes constitutive activation of the proto-oncogeneCorrect answer
  2. B.Temporary reduction in the rate of DNA replication during normal cell division
  3. C.Increased production of antibodies against extracellular pathogens
  4. D.Complete stoppage of protein synthesis in all normal cells

Solution

Proto-oncogenes normally regulate cell growth and division. Mutations or other genetic alterations that make them constitutively active can convert them into oncogenes, leading to uncontrolled proliferation and cancer development.

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