Endocrinology & Reproduction · NEET PG Preparation Physiology
A researcher is studying the intracellular mechanisms of various peptide and steroid hormones in an endocrine lab. Which of the following hormones ut…
Practice question from Endocrinology & Reproduction (NEET PG Preparation Physiology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-1F7C00
A researcher is studying the intracellular mechanisms of various peptide and steroid hormones in an endocrine lab. Which of the following hormones utilizes a receptor that inherently possesses intrinsic tyrosine kinase activity upon ligand binding?
- A.Thyroid-stimulating hormone (TSH)
- B.InsulinCorrect answer
- C.Adrenocorticotropic hormone (ACTH)
- D.Antidiuretic hormone (ADH)
Solution
Insulin binds to a receptor tyrosine kinase (RTK). Upon binding, the receptor autophosphorylates its intracellular domain, recruiting insulin receptor substrates (IRS) to mediate metabolic and mitogenic effects. TSH, ACTH, and ADH utilize G-protein coupled receptors (GPCRs).
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