Mycology · NEET PG Preparation Microbiology
A 22-year-old immigrant from the Ohio River Valley presents with fever, weight loss, and hepatosplenomegaly. A bone marrow aspirate is performed, and…
Practice question from Mycology (NEET PG Preparation Microbiology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-208939
A 22-year-old immigrant from the Ohio River Valley presents with fever, weight loss, and hepatosplenomegaly. A bone marrow aspirate is performed, and intracellular yeast cells are seen within macrophages, resembling small oval yeasts with a narrow-based bud. The fungus responsible for this infection is:
- A.Blastomyces dermatitidis
- B.Histoplasma capsulatumCorrect answer
- C.Coccidioides immitis
- D.Paracoccidioides brasiliensis
Solution
Histoplasma capsulatum is endemic to the Ohio and Mississippi river valleys. In tissue, it is characteristically found intracellularly within reticuloendothelial cells (macrophages) as small yeast cells measuring 2-4 micrometers with a narrow-based bud.
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