Gynaecological Oncology · NEET PG Preparation Obstetrics & Gynaecology
A 22-year-old nulliparous female presents with a rapidly growing, painful solid-cystic right ovarian mass. Serum tumor markers show elevated alpha-fe…
Practice question from Gynaecological Oncology (NEET PG Preparation Obstetrics & Gynaecology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-2B9219
A 22-year-old nulliparous female presents with a rapidly growing, painful solid-cystic right ovarian mass. Serum tumor markers show elevated alpha-fetoprotein (AFP) and normal beta-hCG and CA-125. She undergoes a fertility-sparing right salpingo-oophorectomy and surgical staging. Histology reveals a malignant germ cell tumor. Which of the following is the most likely diagnosis?
- A.Dysgerminoma
- B.Immature teratoma
- C.Yolk sac tumor (Endodermal sinus tumor)Correct answer
- D.Granulosa cell tumor
Solution
Yolk sac tumors (endodermal sinus tumors) are malignant ovarian germ cell tumors characterized by significantly elevated serum alpha-fetoprotein (AFP) levels. They commonly affect children and young adults and typically present with rapid growth and pelvic pain.
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