Gynaecological Oncology · NEET PG Preparation Obstetrics & Gynaecology
A 62-year-old postmenopausal woman presents with a complex pelvic mass, ascites, and an elevated CA-125 level. She undergoes an exploratory laparotom…
Practice question from Gynaecological Oncology (NEET PG Preparation Obstetrics & Gynaecology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-F061A9
A 62-year-old postmenopausal woman presents with a complex pelvic mass, ascites, and an elevated CA-125 level. She undergoes an exploratory laparotomy, total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and optimal debulking. Histopathology confirms high-grade serous carcinoma of the ovary, staged as IIIC. What is the standard first-line adjuvant systemic therapy?
- A.Bleomycin, Etoposide, and Cisplatin (BEP)
- B.Paclitaxel and CarboplatinCorrect answer
- C.Tamoxifen and Megestrol acetate
- D.Methotrexate and Leucovorin rescue
Solution
The standard first-line chemotherapy regimen for advanced epithelial ovarian cancer is intravenous combination therapy with paclitaxel and carboplatin, typically given for 6 cycles. BEP is used for germ cell tumors, not epithelial ovarian carcinomas.
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