Neurology · NEET PG Preparation Medicine
A 45-year-old woman presents with double vision and drooping of her left eyelid, which worsens toward the end of the day and improves after rest. On…
Practice question from Neurology (NEET PG Preparation Medicine), with the correct answer and a step-by-step solution.
easy · MCQ · Q-2ED23F
A 45-year-old woman presents with double vision and drooping of her left eyelid, which worsens toward the end of the day and improves after rest. On examination, there is left-sided ptosis and weakness of upward gaze, which fatigues on sustained upward looking. Ice pack application to the left eye significantly improves the ptosis. Which of the following autoantibodies is most specific for this condition?
- A.Anti-acetylcholine receptor antibodiesCorrect answer
- B.Anti-muscle-specific kinase (MuSK) antibodies
- C.Anti-voltage-gated calcium channel antibodies
- D.Anti-glutamic acid decarboxylase antibodies
Solution
This is a classic clinical presentation of Myasthenia Gravis. Anti-acetylcholine receptor (AChR) antibodies are the most specific and sensitive antibodies found in generalized myasthenia gravis. Anti-VGCC antibodies are associated with Lambert-Eaton myasthenic syndrome.
More from Neurology
- A 62-year-old man presents with progressive weakness and muscle wasting in his right hand for the past 4 months, followed by similar involv…
- A 28-year-old woman presents with episodes of severe, throbbing right-sided headaches lasting 12 hours, associated with nausea, vomiting, p…
- A 55-year-old chronic alcoholic man is brought to the emergency department in a confused state. Examination reveals ophthalmoparesis, horiz…
- A 70-year-old man presents with progressive memory loss, gait disturbances, and urinary incontinence over the past 6 months. Magnetic reson…
Practise more Medicine
Sign up free for adaptive practice on this chapter, with instant feedback and hints on every question.
Start practising freeFree to start · No credit card needed