Neurology · NEET PG Preparation Medicine
A 70-year-old man presents with progressive memory loss, gait disturbances, and urinary incontinence over the past 6 months. Magnetic resonance imagi…
Practice question from Neurology (NEET PG Preparation Medicine), with the correct answer and a step-by-step solution.
medium · MCQ · Q-51C296
A 70-year-old man presents with progressive memory loss, gait disturbances, and urinary incontinence over the past 6 months. Magnetic resonance imaging of the brain shows marked ventriculomegaly that is disproportionate to the degree of cerebral cortical atrophy, along with stretching of the corpus callosum. Lumbar puncture opening pressure is normal. What is the most likely diagnosis?
- A.Alzheimer disease
- B.Normal pressure hydrocephalusCorrect answer
- C.Huntington disease
- D.Creutzfeldt-Jakob disease
Solution
Normal pressure hydrocephalus (NPH) classically presents with the triad of gait disturbance (often described as magnetic or apraxic gait), urinary incontinence, and cognitive impairment (dementia). MRI reveals disproportionately enlarged ventricles without prominent sulcal widening (out of proportion to sulcal atrophy). Treatment involves placement of a ventriculoperitoneal shunt.
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