Medical Disorders in Pregnancy · NEET PG Preparation Obstetrics & Gynaecology
A 26-year-old primigravida at 16 weeks of gestation is diagnosed with overt hypothyroidism. Her thyroid-stimulating hormone (TSH) is 8.5 mIU/L and fr…
Practice question from Medical Disorders in Pregnancy (NEET PG Preparation Obstetrics & Gynaecology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-2F1A82
A 26-year-old primigravida at 16 weeks of gestation is diagnosed with overt hypothyroidism. Her thyroid-stimulating hormone (TSH) is 8.5 mIU/L and free T4 is low. She is started on levothyroxine replacement. Which of the following is the primary goal of maintaining optimal maternal thyroid hormone levels during pregnancy?
- A.Prevention of maternal postpartum hemorrhage
- B.Prevention of fetal neurodevelopmental impairment and cretinismCorrect answer
- C.Prevention of gestational trophoblastic disease
- D.Prevention of maternal gestational diabetes mellitus
Solution
During the first half of pregnancy, the fetus relies entirely on maternal thyroid hormones for brain development, as the fetal thyroid gland does not function until the late first/early second trimester. Maternal hypothyroidism, if uncorrected, significantly increases the risk of impaired neurodevelopment, lower IQ, and cretinism in the offspring.
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