Medical Disorders in Pregnancy · NEET PG Preparation Obstetrics & Gynaecology
A 25-year-old primigravida at 12 weeks of gestation is screened for viral hepatitis as part of routine antenatal care. Her laboratory results show: H…
Practice question from Medical Disorders in Pregnancy (NEET PG Preparation Obstetrics & Gynaecology), with the correct answer and a step-by-step solution.
hard · MCQ · Q-79C695
A 25-year-old primigravida at 12 weeks of gestation is screened for viral hepatitis as part of routine antenatal care. Her laboratory results show: HBsAg positive, HBeAg positive, and Anti-HBc IgM negative. What is the recommended prophylaxis for the newborn immediately after birth to prevent vertical transmission of Hepatitis B?
- A.Hepatitis B vaccine only within 7 days of birth
- B.Hepatitis B immunoglobulin (HBIG) and Hepatitis B vaccine within 12 hours of birthCorrect answer
- C.Antiviral therapy to the mother and no intervention for the neonate
- D.Hepatitis B immunoglobulin (HBIG) alone at 4 weeks of age
Solution
Infants born to HBsAg-positive mothers (especially those who are HBeAg-positive, indicating high viral load and infectivity) should receive both Hepatitis B immune globulin (HBIG) and the first dose of the Hepatitis B vaccine at separate injection sites within 12 hours of birth to maximally prevent vertical transmission.
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