Physiology of Pregnancy & Antenatal Care · NEET PG Preparation Obstetrics & Gynaecology
A 26-year-old primigravida at 12 weeks of gestation presents for her first routine antenatal visit. Which of the following physiological hematologica…
Practice question from Physiology of Pregnancy & Antenatal Care (NEET PG Preparation Obstetrics & Gynaecology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-455B47
A 26-year-old primigravida at 12 weeks of gestation presents for her first routine antenatal visit. Which of the following physiological hematological changes is expected during a normal, uncomplicated pregnancy?
- A.Increase in hemoglobin concentration due to erythropoiesis
- B.Decrease in total leukocyte count (TLC)
- C.Increase in plasma volume greater than the increase in red cell massCorrect answer
- D.Decrease in erythrocyte sedimentation rate (ESR)
Solution
During normal pregnancy, plasma volume increases by about 40-50%, while red cell mass increases by only 20-30%. This disproportionate increase leads to hemodilution and a physiological 'anaemia of pregnancy' characterized by a drop in hemoglobin and hematocrit. The total leukocyte count increases due to neutrophilia, and the ESR is markedly elevated due to increased plasma fibrinogen.
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