Uvea · NEET PG Preparation Ophthalmology
Which of the following human leukocyte antigens (HLA) is most strongly associated with acute anterior uveitis linked to ankylosing spondylitis and ot…
Practice question from Uvea (NEET PG Preparation Ophthalmology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-533FAF
Which of the following human leukocyte antigens (HLA) is most strongly associated with acute anterior uveitis linked to ankylosing spondylitis and other seronegative spondyloarthropathies?
- A.HLA-B51
- B.HLA-B27Correct answer
- C.HLA-A29
- D.HLA-DR4
Solution
HLA-B27 is strongly associated with acute non-granulomatous anterior uveitis, commonly seen in association with ankylosing spondylitis, reactive arthritis, inflammatory bowel disease, and psoriatic arthritis. HLA-B51 is associated with Behcet disease, and HLA-A29 is associated with birdshot retinochoroidopathy.
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