Gastrointestinal Physiology · NEET PG Preparation Physiology
Fat digestion and absorption depend critically on the formation of micelles in the intestinal lumen. Which of the following components is primarily r…
Practice question from Gastrointestinal Physiology (NEET PG Preparation Physiology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-5979F1
Fat digestion and absorption depend critically on the formation of micelles in the intestinal lumen. Which of the following components is primarily responsible for the hydrophilic outer shell of a mixed micelle?
- A.Triglycerides
- B.Cholesterol esters
- C.Bile saltsCorrect answer
- D.Fat-soluble vitamins
Solution
Bile salts are amphipathic molecules possessing both hydrophobic (lipid-soluble) and hydrophilic (water-soluble) regions. In the intestinal lumen, they orient themselves with their hydrophilic surfaces facing outward toward the aqueous intestinal contents and hydrophobic surfaces facing inward, solubilizing lipolytic products into mixed micelles.
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