Muscle Relaxants · NEET PG Preparation Anaesthesia
Which of the following non-depolarizing muscle relaxants undergoes Hofmann elimination, making it the agent of choice in patients with severe hepatic…
Practice question from Muscle Relaxants (NEET PG Preparation Anaesthesia), with the correct answer and a step-by-step solution.
medium · MCQ · Q-5AAF50
Which of the following non-depolarizing muscle relaxants undergoes Hofmann elimination, making it the agent of choice in patients with severe hepatic and renal failure?
- A.Pancuronium
- B.Vecuronium
- C.CisatracuriumCorrect answer
- D.Rocuronium
Solution
Cisatracurium (an isomer of atracurium) undergoes spontaneous degradation at physiological pH and temperature via Hofmann elimination, independent of liver and kidney function. This makes it ideal for patients with end-stage renal or hepatic disease.
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