Respiratory Medicine · NEET PG Preparation Medicine
A 32-year-old man presents with recurrent episodes of wheezing, fleeting pulmonary infiltrates on chest radiography, and peripheral blood eosinophili…
Practice question from Respiratory Medicine (NEET PG Preparation Medicine), with the correct answer and a step-by-step solution.
hard · MCQ · Q-6BED4A
A 32-year-old man presents with recurrent episodes of wheezing, fleeting pulmonary infiltrates on chest radiography, and peripheral blood eosinophilia. Total serum IgE is markedly elevated, and skin test is positive for Aspergillus fumigatus antigens. Which of the following is the hallmark diagnostic finding for Allergic Bronchopulmonary Aspergillosis (ABPA)?
- A.Central bronchiectasisCorrect answer
- B.Panacinar emphysema
- C.Peribronchial honeycombing in the lower lobes
- D.Pleural plaques with calcification
Solution
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction to Aspergillus fumigatus colonization in the airways of patients with asthma or cystic fibrosis. A hallmark radiological finding is central (proximal) bronchiectasis, typically affecting upper lobes, in contrast to smoking-related COPD or post-infectious bronchiectasis which often affects peripheral or lower airways.
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