Environment & Occupational Health · NEET PG Preparation Community Medicine (PSM)

A 45-year-old male worker in a battery manufacturing unit presents with wrist drop, colicky abdominal pain, and a dark blue line along the gingival m…

Practice question from Environment & Occupational Health (NEET PG Preparation Community Medicine (PSM)), with the correct answer and a step-by-step solution.

medium · MCQ · Q-73C13B

A 45-year-old male worker in a battery manufacturing unit presents with wrist drop, colicky abdominal pain, and a dark blue line along the gingival margin. Laboratory investigations reveal microcytic hypochromic anemia with basophilic stippling. Which of the following is the most sensitive screening test for occupational exposure to this toxic metal?

  1. A.Blood lead level
  2. B.Blood delta-aminolevulinic acid dehydratase (ALAD) activityCorrect answer
  3. C.Urinary coproporphyrin
  4. D.Free erythrocyte protoporphyrin (FEP)

Solution

Blood delta-aminolevulinic acid dehydratase (ALAD) activity is the most sensitive biomarker for early biological effect and exposure to lead, as it is inhibited at very low blood lead concentrations.

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