Epidemiology & Screening · NEET PG Preparation Community Medicine (PSM)

A new diagnostic test for typhoid fever is evaluated against blood culture (gold standard). Out of 200 confirmed typhoid patients, 160 test positive.…

Practice question from Epidemiology & Screening (NEET PG Preparation Community Medicine (PSM)), with the correct answer and a step-by-step solution.

medium · MCQ · Q-796B60

A new diagnostic test for typhoid fever is evaluated against blood culture (gold standard). Out of 200 confirmed typhoid patients, 160 test positive. Out of 300 non-typhoid patients, 60 test positive. What is the sensitivity and specificity of the test, respectively?

  1. A.80% and 80%Correct answer
  2. B.80% and 60%
  3. C.60% and 80%
  4. D.90% and 70%

Solution

Sensitivity is the ability of a test to correctly identify those with the disease (True Positives / All Diseased) = 160/200=80%160 / 200 = 80\%. Specificity is the ability to correctly identify those without the disease (True Negatives / All Non-Diseased). Total non-diseased = 300, False positives = 60, so True Negatives = 300−60=240300 - 60 = 240. Specificity = 240/300=80%240 / 300 = 80\%.

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