Biostatistics · NEET PG Preparation Community Medicine (PSM)
During a screening program for diabetes, a new rapid test is evaluated against the gold standard oral glucose tolerance test. If the cutoff value of…
Practice question from Biostatistics (NEET PG Preparation Community Medicine (PSM)), with the correct answer and a step-by-step solution.
hard · MCQ · Q-8AE43E
During a screening program for diabetes, a new rapid test is evaluated against the gold standard oral glucose tolerance test. If the cutoff value of the rapid test is increased to reduce false positives, what will be the inevitable effect on its sensitivity and specificity?
- A.Sensitivity increases, specificity decreases
- B.Sensitivity decreases, specificity increasesCorrect answer
- C.Both sensitivity and specificity increase
- D.Both sensitivity and specificity decrease
Solution
Raising the cutoff threshold makes it harder for anyone to test positive. This decreases true positives (thus decreasing sensitivity) and increases true negatives / decreases false positives (thus increasing specificity).
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