Gastroenterology & Hepatology · NEET PG Preparation Medicine
A 45-year-old chronic alcoholic male presents with massive hematemesis. On examination, he has jaundice, massive ascites, and asterixis. Upper GI end…
Practice question from Gastroenterology & Hepatology (NEET PG Preparation Medicine), with the correct answer and a step-by-step solution.
easy · MCQ · Q-9F8C56
A 45-year-old chronic alcoholic male presents with massive hematemesis. On examination, he has jaundice, massive ascites, and asterixis. Upper GI endoscopy reveals actively bleeding esophageal varices. Which of the following is the most effective initial pharmacological therapy to control acute variceal bleeding?
- A.TerlipressinCorrect answer
- B.Propranolol
- C.Spironolactone
- D.Lactulose
Solution
Terlipressin is a vasopressin analogue that causes splanchnic vasoconstriction, thereby reducing portal venous pressure. It is one of the standard first-line pharmacological agents used along with endoscopic therapy in acute variceal hemorrhage. Propranolol is used for primary and secondary prophylaxis, not acute bleeding.
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