Gastroenterology & Hepatology · NEET PG Preparation Medicine
A 28-year-old male presents with chronic, recurrent abdominal pain, non-bloody diarrhea, and low-grade fever. Colonoscopy reveals patchy areas of inf…
Practice question from Gastroenterology & Hepatology (NEET PG Preparation Medicine), with the correct answer and a step-by-step solution.
easy · MCQ · Q-A1DBB7
A 28-year-old male presents with chronic, recurrent abdominal pain, non-bloody diarrhea, and low-grade fever. Colonoscopy reveals patchy areas of inflammation with cobblestone appearance, deep linear ulcers, and skip lesions involving the terminal ileum. Biopsy shows transmural inflammation and non-caseating granulomas. What is the most likely diagnosis?
- A.Crohn diseaseCorrect answer
- B.Ulcerative colitis
- C.Intestinal tuberculosis
- D.Ischemic colitis
Solution
Crohn disease is characterized by skip lesions, transmural inflammation, cobblestoning, and non-caseating granulomas (found in roughly 30% of biopsies), most frequently affecting the terminal ileum. Ulcerative colitis is limited to the mucosa/submucosa, starts in the rectum, and has continuous mucosal involvement without granulomas.
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