Radiotherapy & Nuclear Medicine · NEET PG Preparation Radiology
In the evaluation of suspected neuroendocrine tumors, which of the following radiotracers is most specific and sensitive for molecular imaging via PE…
Practice question from Radiotherapy & Nuclear Medicine (NEET PG Preparation Radiology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-A88463
In the evaluation of suspected neuroendocrine tumors, which of the following radiotracers is most specific and sensitive for molecular imaging via PET-CT?
- A.Fluorodeoxyglucose (18F-FDG)
- B.Gallium-68 DOTATATECorrect answer
- C.Technetium-99m MDP
- D.Gallium-68 PSMA
Solution
Gallium-68 DOTATATE binds with high affinity to somatostatin receptors (specifically subtype 2), which are overexpressed on the surface of well-differentiated neuroendocrine tumors. 18F-FDG is generally less sensitive for low-grade neuroendocrine tumors, whereas Ga-68 PSMA is used for prostate cancer, and Tc-99m MDP is used for bone scintigraphy.
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