Breast & Endocrine Surgery · NEET PG Preparation Surgery

A 45-year-old woman undergoes core needle biopsy for a suspicious microcalcification cluster on mammography, which confirms Ductal Carcinoma In Situ…

Practice question from Breast & Endocrine Surgery (NEET PG Preparation Surgery), with the correct answer and a step-by-step solution.

medium · MCQ · Q-0B2D35

A 45-year-old woman undergoes core needle biopsy for a suspicious microcalcification cluster on mammography, which confirms Ductal Carcinoma In Situ (DCIS). What is the single most important factor determining the risk of local recurrence after breast-conserving surgery for DCIS?

  1. A.Patient age
  2. B.Surgical margin statusCorrect answer
  3. C.Presence of comedonecrosis
  4. D.Nuclear grade

Solution

Surgical margin status is the most critical determinant of local recurrence following breast-conserving surgery for DCIS. Achieving clear margins (typically at least 2 mm) significantly decreases the rate of local recurrence, regardless of other biological features like grade or comedonecrosis.

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