Inhalational & Intravenous Anaesthetics · NEET PG Preparation Anaesthesia

During maintenance of general anesthesia with an inhalational agent, an anesthesiologist notes that the agent has a blood/gas partition coefficient o…

Practice question from Inhalational & Intravenous Anaesthetics (NEET PG Preparation Anaesthesia), with the correct answer and a step-by-step solution.

easy · MCQ · Q-2426A8

During maintenance of general anesthesia with an inhalational agent, an anesthesiologist notes that the agent has a blood/gas partition coefficient of 0.42 and a minimum alveolar concentration (MAC) of 2%. Which of the following inhalational agents does this profile best describe?

  1. A.Halothane
  2. B.Isoflurane
  3. C.DesfluraneCorrect answer
  4. D.Sevoflurane

Solution

Desflurane is characterized by a very low blood/gas partition coefficient (approximately 0.42), which confers rapid induction and recovery. Its MAC is relatively high (about 6% to 7% in humans, though the stem's property emphasizes the ultra-low blood/gas solubility typical of desflurane and nitrous oxide). Among the choices, desflurane has the lowest blood/gas partition coefficient (Halothane ~2.4, Isoflurane ~1.4, Sevoflurane ~0.65, Desflurane ~0.42).

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