Molecular Biology & Genetics · NEET PG Preparation Biochemistry
Which of the following eukaryotic translation initiation factors (eIFs) is responsible for recognizing the 7-methylguanosine cap structure of mRNA?
Practice question from Molecular Biology & Genetics (NEET PG Preparation Biochemistry), with the correct answer and a step-by-step solution.
medium · MCQ · Q-375F70
Which of the following eukaryotic translation initiation factors (eIFs) is responsible for recognizing the 7-methylguanosine cap structure of mRNA?
- A.eIF2
- B.eIF4ECorrect answer
- C.eIF4A
- D.eIF6
Solution
eIF4E is the cap-binding protein that specifically recognizes and binds to the 7-methylguanosine cap at the 5' end of eukaryotic mRNA. eIF2 brings the initiator Met-tRNA to the 40S ribosomal subunit. eIF4A is an RNA helicase. eIF6 prevents premature joining of ribosomal subunits.
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