Cardiovascular & Renal Drugs · NEET PG Preparation Pharmacology
Which of the following diuretics acts primarily by inhibiting the Na+-K+-2Cl- symporter in the thick ascending limb of the loop of Henle and is most…
Practice question from Cardiovascular & Renal Drugs (NEET PG Preparation Pharmacology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-3E098E
Which of the following diuretics acts primarily by inhibiting the Na+-K+-2Cl- symporter in the thick ascending limb of the loop of Henle and is most commonly associated with ototoxicity?
- A.Hydrochlorothiazide
- B.Spironolactone
- C.FurosemideCorrect answer
- D.Acetazolamide
Solution
Furosemide is a loop diuretic that inhibits the Na+-K+-2Cl- cotransporter in the thick ascending limb of the loop of Henle. Loop diuretics can cause ototoxicity due to alterations in the electrolyte composition of the endolymph in the inner ear.
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