A 28-year-old male is evaluated for prominent negative symptoms of schizophrenia, including avolition, alogia, and asociality, which have shown poor…

Among typical and atypical agents, selective serotonin inverse agonism at 5-HT2A receptors is characteristic of agents like pimavanserin (used in Parkinson's psychosis). However, among standard atypical antipsychotics, high 5-HT2A/D2 affinity ratio is the hallmark mechanism. Looking at the options, haloperidol is a high-potency typical D2 blocker, aripiprazole is a partial D2 agonist, mirtazapine is an antidepressant. Pimavanserin is a selective inverse agonist at 5-HT2A receptors. Wait, reviewing the choices: standard atypical antipsychotics like olanzapine, risperidone, quetiapine have high 5-HT2A to D2 affinity. Let's re-evaluate standard atypical profile. Since the question highlights 5-HT2A relative to D2, let's use a cleaner question or verify standard options. Let's make sure the options are standard: A) Haloperidol, B) Chlorpromazine, C) Quetiapine, D) Pimozide. Wait, atypical antipsychotics include quetiapine. Let's adjust the question text and options to match standard INI-CET pattern.