Schizophrenia & Psychosis · NEET PG Preparation Psychiatry
A 32-year-old man with a 5-year history of treatment-resistant schizophrenia, characterized by persistent persecutory delusions and auditory hallucin…
Practice question from Schizophrenia & Psychosis (NEET PG Preparation Psychiatry), with the correct answer and a step-by-step solution.
easy · MCQ · Q-C06C6F
A 32-year-old man with a 5-year history of treatment-resistant schizophrenia, characterized by persistent persecutory delusions and auditory hallucinations despite adequate trials of two different atypical antipsychotics (including olanzapine and risperidone), is considered for clozapine therapy. Which of the following baseline hematological investigations is mandatory before initiating clozapine treatment?
- A.Absolute Neutrophil Count (ANC) and total leukocyte countCorrect answer
- B.Erythrocyte Sedimentation Rate (ESR)
- C.Reticulocyte count
- D.Serum ferritin level
Solution
Clozapine is associated with a risk of agranulocytosis. Baseline and regular monitoring of the Absolute Neutrophil Count (ANC) and total leukocyte count are mandatory before and during treatment to ensure patient safety.
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