Haematology · NEET PG Preparation Pathology
A bone marrow aspirate from a 60-year-old patient with pancytopenia shows 35% myeloblasts containing distinct red-purple, needle-like cytoplasmic inc…
Practice question from Haematology (NEET PG Preparation Pathology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-5D5DB9
A bone marrow aspirate from a 60-year-old patient with pancytopenia shows 35% myeloblasts containing distinct red-purple, needle-like cytoplasmic inclusions. Cytochemical staining shows these inclusions and the surrounding cytoplasm are strongly positive for myeloperoxidase (MPO) and Sudan Black B. Which of the following are these inclusions called?
- A.Dohle bodies
- B.Auer rodsCorrect answer
- C.Russell bodies
- D.Heinz bodies
Solution
Auer rods are abnormal azurophilic granules that fuse together in the cytoplasm of myeloblasts in acute myeloid leukemia (AML). They are diagnostic of myeloid differentiation and stain positively for MPO.
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