Immunology · NEET PG Preparation Microbiology
Which of the following interleukins is the primary growth, survival, and differentiation factor for naive T cells and is essential for the generation…
Practice question from Immunology (NEET PG Preparation Microbiology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-7D152A
Which of the following interleukins is the primary growth, survival, and differentiation factor for naive T cells and is essential for the generation and maintenance of regulatory T cells (Tregs)?
- A.Interleukin-1 (IL-1)
- B.Interleukin-2 (IL-2)Correct answer
- C.Interleukin-4 (IL-4)
- D.Interleukin-17 (IL-17)
Solution
Interleukin-2 (IL-2) is produced mainly by activated T cells and acts in an autocrine and paracrine manner to promote proliferation, survival, and differentiation of T cells. It is also crucially required for the development, survival, and peripheral homeostasis of CD4+CD25+FOXP3+ regulatory T cells.
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