CNS Drugs · NEET PG Preparation Pharmacology
A 35-year-old male with treatment-resistant schizophrenia is started on clozapine. Which of the following life-threatening adverse effects requires m…
Practice question from CNS Drugs (NEET PG Preparation Pharmacology), with the correct answer and a step-by-step solution.
easy · MCQ · Q-7FD645
A 35-year-old male with treatment-resistant schizophrenia is started on clozapine. Which of the following life-threatening adverse effects requires mandatory weekly blood monitoring during the first 18 weeks of therapy?
- A.AgranulocytosisCorrect answer
- B.Torsades de pointes
- C.Hepatotoxicity
- D.Pulmonary fibrosis
Solution
Clozapine carries a significant risk of severe neutropenia and agranulocytosis. Due to this potentially fatal adverse effect, strict hematological monitoring (white blood cell count and absolute neutrophil count) is mandatory.
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