STDs & Pigmentary Disorders · NEET PG Preparation Dermatology
A 24-year-old male presents with multiple painful vesicular and ulcerative lesions on the genitalia, accompanied by tender inguinal lymphadenopathy a…
Practice question from STDs & Pigmentary Disorders (NEET PG Preparation Dermatology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-897328
A 24-year-old male presents with multiple painful vesicular and ulcerative lesions on the genitalia, accompanied by tender inguinal lymphadenopathy and systemic symptoms including fever and malaise. Tzanck smear from the base of an ulcer reveals multinucleated giant cells. What is the most definitive diagnostic test for this condition?
- A.Venereal Disease Research Laboratory (VDRL) test
- B.Polymerase chain reaction (PCR) or viral cultureCorrect answer
- C.Dark-field microscopy
- D.Gram stain showing gram-negative rods in 'school of fish' pattern
Solution
The clinical presentation and Tzanck smear showing multinucleated giant cells are classic for Herpes Genitalis caused by Herpes Simplex Virus (HSV). PCR is currently the most sensitive and definitive diagnostic method.
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