STDs & Pigmentary Disorders · NEET PG Preparation Dermatology
A 30-year-old woman presents with progressive, well-demarcated depigmented patches over the dorsal hands, face, and knees. Wood's lamp examination re…
Practice question from STDs & Pigmentary Disorders (NEET PG Preparation Dermatology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-CF9002
A 30-year-old woman presents with progressive, well-demarcated depigmented patches over the dorsal hands, face, and knees. Wood's lamp examination reveals blue-white fluorescence of the lesions. Histopathological examination of a lesional skin biopsy will most characteristically show:
- A.Increased number of melanocytes in the basal layer
- B.Complete absence of melanocytes in the epidermisCorrect answer
- C.Normal number of melanocytes with increased melanin clumping
- D.Dense dermal infiltrate of melanin-laden macrophages
Solution
Vitiligo is an acquired depigmentary disorder characterized by the destruction and complete absence of functional melanocytes in the epidermis of lesional skin.
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