Virology · NEET PG Preparation Microbiology
A 25-year-old medical student sustains a needle-stick injury while drawing blood from a patient known to be HBsAg-positive and HBeAg-positive. The st…
Practice question from Virology (NEET PG Preparation Microbiology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-8E68A2
A 25-year-old medical student sustains a needle-stick injury while drawing blood from a patient known to be HBsAg-positive and HBeAg-positive. The student's baseline anti-HBs titer is < 10 IU/L. According to CDC guidelines, what is the most appropriate post-exposure prophylaxis?
- A.Hepatitis B immune globulin (HBIG) only
- B.Hepatitis B vaccine series only
- C.Both HBIG and initiation of the Hepatitis B vaccine seriesCorrect answer
- D.Observation and repeat serology in 6 months
Solution
For an unvaccinated or non-responder individual (anti-HBs < 10 IU/L) exposed to an HBsAg-positive source, the recommended post-exposure prophylaxis is both Hepatitis B immune globulin (HBIG) for immediate passive immunity and initiation of the Hepatitis B vaccine series.
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