Antimicrobials · NEET PG Preparation Pharmacology
A patient with severe hospital-acquired pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA) is treated with vancomycin. Therapeutic d…
Practice question from Antimicrobials (NEET PG Preparation Pharmacology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-93E00C
A patient with severe hospital-acquired pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA) is treated with vancomycin. Therapeutic drug monitoring is essential because vancomycin toxicity primarily manifests as:
- A.Aplastic anemia and gray baby syndrome
- B.Nephrotoxicity and ototoxicityCorrect answer
- C.Disulfiram-like reaction and severe hypoglycemia
- D.Pulmonary fibrosis and optic neuritis
Solution
Vancomycin is a glycopeptide antibiotic whose major serious adverse effects are nephrotoxicity and ototoxicity, especially when trough levels are too high or when combined with other nephrotoxic agents like aminoglycosides.
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