Vitamins & Minerals · NEET PG Preparation Biochemistry

A 3-year-old child presents with night blindness and Bitot spots on the conjunctiva. Dietary history reveals a predominantly cereal-based diet lackin…

Practice question from Vitamins & Minerals (NEET PG Preparation Biochemistry), with the correct answer and a step-by-step solution.

easy · MCQ · Q-97A315

A 3-year-old child presents with night blindness and Bitot spots on the conjunctiva. Dietary history reveals a predominantly cereal-based diet lacking green leafy vegetables and animal products. Which of the following intracellular processes is primarily dependent on the active metabolite of the deficient vitamin?

  1. A.Gamma-carboxylation of clotting factors
  2. B.Glycoprotein synthesis and cellular differentiationCorrect answer
  3. C.Collagen hydroxylation
  4. D.Calcium and phosphate reabsorption in the renal tubules

Solution

The child has Vitamin A deficiency manifesting as night blindness and Bitot spots. Retinoic acid is essential for the maintenance of epithelial tissues and glycoprotein synthesis via functioning as a hormone that regulates gene transcription.

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