Renal & GI Pathology · NEET PG Preparation Pathology
A 55-year-old chronic smoker presents with painless gross hematuria and a left-sided varicocele that does not recumbent. Radical nephrectomy is perfo…
Practice question from Renal & GI Pathology (NEET PG Preparation Pathology), with the correct answer and a step-by-step solution.
medium · MCQ · Q-1E84CF
A 55-year-old chronic smoker presents with painless gross hematuria and a left-sided varicocele that does not recumbent. Radical nephrectomy is performed. Histological examination reveals tumor cells with abundant clear cytoplasm and well-defined cell borders separated by a network of branching capillaries. What is the cell of origin for this renal cell carcinoma subtype?
- A.Distal convoluted tubule
- B.Proximal convoluted tubuleCorrect answer
- C.Collecting duct
- D.Juxtaglomerular apparatus
Solution
The histological description is characteristic of clear cell renal cell carcinoma, which is the most common subtype of renal cell carcinoma and originates from the epithelial cells of the proximal convoluted tubules.
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