Psychopharmacology · NEET PG Preparation Psychiatry

A 45-year-old woman with bipolar disorder type I is brought to the emergency department with coarse tremors, ataxia, vomiting, and confusion. Her ser…

Practice question from Psychopharmacology (NEET PG Preparation Psychiatry), with the correct answer and a step-by-step solution.

hard · MCQ · Q-3DF455

A 45-year-old woman with bipolar disorder type I is brought to the emergency department with coarse tremors, ataxia, vomiting, and confusion. Her serum lithium level is found to be 2.2 mEq/L. Which of the following is the most definitive management step in severe lithium toxicity when conservative measures fail or levels are extremely high?

  1. A.Administer intravenous normal saline and furosemide
  2. B.Perform hemodialysisCorrect answer
  3. C.Administer sodium polystyrene sulfonate (Kayexalate)
  4. D.Administer flumazenil intravenously

Solution

Severe lithium toxicity (levels > 2.0 mEq/L with severe neurological symptoms or renal impairment) is an indication for hemodialysis, as lithium is dialyzable due to its low molecular weight and minimal protein binding.

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