Psychopharmacology · NEET PG Preparation Psychiatry
A 35-year-old male with treatment-resistant schizophrenia is started on clozapine. Which of the following baseline investigations is mandatory before…
Practice question from Psychopharmacology (NEET PG Preparation Psychiatry), with the correct answer and a step-by-step solution.
medium · MCQ · Q-55D786
A 35-year-old male with treatment-resistant schizophrenia is started on clozapine. Which of the following baseline investigations is mandatory before initiating this medication, according to standard safety monitoring guidelines?
- A.Serum creatinine and blood urea nitrogen
- B.Absolute neutrophil count (ANC) and total leukocyte count (TLC)Correct answer
- C.Thyroid function tests (TSH and free T4)
- D.Serum lithium levels
Solution
Clozapine carries a significant risk of agranulocytosis. Therefore, monitoring of the absolute neutrophil count (ANC) and total leukocyte count (TLC) is mandatory before initiation and regularly throughout treatment.
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